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London, chief city of Airstrip One, the third most populous province of Oceania. It's 1984 and Julia Worthing works as a mechanic fixing the novel-writing machines in the Fiction Department at the Ministry of Truth. Under the ideology of IngSoc and the rule of the Party and its leader Big Brother, Julia is a model citizen - cheerfully cynical, believing in nothing and caring not at all about politics. She routinely breaks the rules but also collaborates with the regime whenever necessary. Everyone likes Julia.

Jane Pearson is camping with her husband Leo and their five-year-old son Benjamin, deep in the California woods on an evening in late August. At the moment that she drifts to sleep outside the tent where Leo and Benjamin are preparing for bed, every single person with a Y chromosome vanishes from the world, disappearing from operating theatres mid-surgery, from behind the wheels of cars, from arguments and acts of love. Children, adults, even fetuses are gone in an instant. Leo and Benjamin are gone. No one knows why, how, or where.

In the ruins of a future America, 15-year-old Ice Cream Star and her nomadic tribe live off the detritus of a crumbled civilization. Theirs is a world of children; before reaching the age of 20, they all die of a strange disease they call Posies - a plague that has killed for generations. There is no medicine, no treatment, only the mysterious rumor of a cure.

Host Catherine Nichols and guests choose one book for each year of the twentieth century (Nella Larsen's Passing, 1936, Jacqueline Susann's Valley of the Dolls, 1966; Mohandas Gandhi's Indian Home Rule, 1909) and talk about it in its historical and literary context. Tune in to find out what the 20th century was all about.