Machine Biology

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

First coined by Richard Dawkins in The Selfish Gene, a meme is any idea, behavior, or skill that can be transferred from one person to another by imitation. Susan Blackmore shows that once our distant ancestors acquired the crucial ability to imitate, a second kind of natural selection began, a survival of the fittest amongst competing ideas and behaviors. Ideas and behaviors that proved most adaptive-making tools, for example, or using language - survived and flourished, replicating themselves in as many minds as possible.

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

How smart machines are transforming us all - and what we should do about it. The smart machines revolution is reshaping our lives and our societies. Here, Nigel Shadbolt (one of Britain’s leading authorities on artificial intelligence) and Roger Hampson dispel terror, confusion and misconception. We are not about to be elbowed aside by a rebel army of superintelligent robots of our own creation. We were using tools before we became Homo sapiens and will continue to control them. How we exercise that control - in our private lives, in employment, in politics - and make the best of the wonderful opportunities will determine our collective future well-being.

The Age of Living Machines describes some of the most exciting new developments and the scientists and engineers who helped create them. Virus-built batteries. Protein-based water filters. Cancer-detecting nanoparticles. Mind-reading bionic limbs. Computer-engineered crops. Together they highlight the promise of the technology revolution of the 21st century to overcome some of the greatest humanitarian, medical, and environmental challenges of our time.

Imagine living in a world where people use their computers, drive their cars, and communicate with one another simply by thinking. In this stunning and inspiring work, Duke University neuroscientist Miguel Nicolelis shares his revolutionary insights into how the brain creates thought and the human sense of self - and how this might be augmented by machines, so that the entire universe will be within our reach.