Showing titles in Evolution & Genetics

Cancer has always been with us. It killed our hominid ancestors, the mammals they evolved from and the dinosaurs that trampled the ground before that. Tumours grow in pets, livestock and wild animals. Even tiny jelly-like Hydra - creatures that are little more than a tube full of water - can get cancer. Paradoxically, many of us think of cancer as a contemporary killer, a disease of our own making caused by our modern lifestyles.

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean B. Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions.

To the modern mind, the idea of honor is outdated, sexist, and barbaric. It evokes Hamilton and Burr and pistols at dawn, not visions of a well-organized society. But for philosopher Tamler Sommers, a sense of honor is essential to living moral lives. In Why Honor Matters, Sommers argues that our collective rejection of honor has come at great cost. Reliant only on Enlightenment liberalism, the United States has become the home of the cowardly, the shameless, the selfish, and the alienated. Properly channeled, honor encourages virtues like courage, integrity, and solidarity.

More than any other modern scientists, Stephen Jay Gould has opened up to millions the wonders of evolutionary biology. His genius as an essayist lies in his unmatched ability to use his knowledge of the world, including popular culture, to illuminate the realm of science.

Humans, it turns out, are intrinsically wired to seek short-term success at the expense of long-term prosperity. Kristian Rönn, an entrepreneur formerly affiliated with the University of Oxford’s Future of Humanity Institute, calls these deeply rooted impulses “Darwinian demons.” These forces, a by-product of natural selection, can lead us to act in shortsighted ways that harm others—and even imperil our survival as a species. If this evolutionary glitch is left unchecked, the consequences will grow in magnitude as the power of technology accelerates.

The open ocean, far from the shore and miles above the seafloor, is a vast and formidable habitat that is home to the most abundant life on our planet, from giant squid and jellyfish to anglerfish with bioluminescent lures that draw prey into their toothy mouths. Into the Great Wide Ocean takes listeners inside the peculiar world of the seagoing scientists who are providing tantalizing new insights into how the animals of the open ocean solve the problems of their existence.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

Over 500,000 years ago, a single gene mutated. It spread over time, becoming critical in the journey transforming our earliest ancestors into fully modern humans, capable of navigating the entire planet and beyond. Then just a few thousand years ago, humans gradually outsourced knowledge to writing, and we displaced art and music from the heart of learning. This is the extraordinary story of the discovery of a supergene that makes us uniquely human.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

In this engaging exploration, archaeologist Ian Hodder departs from the two prevailing modes of thought about human evolution: the older idea of constant advancement toward a civilized ideal and the newer one of a directionless process of natural selection. Instead, he proposes a theory of human evolution and history based on "entanglement," the ever-increasing mutual dependency between humans and things.

What makes a penguin a bird? Is a camel more closely related to a horse than to a giraffe? Why is a whale not a fish? Similar puzzles preoccupied Charles Darwin throughout his life. Whimsy, in the playfulness of stories for children, is a way to appreciate Darwinian histories. In Do Elephants Have Knees? Charles R. Ault Jr. uses the fanciful imagery of story to explain Darwinian thought. At the same time, he launches careful consideration of Darwin's humanity, the origins of his curiosity, and his ideas.

How is it that a baboon and a blob of slime mould instinctively know what to eat for optimal health, balancing their protein, fat and carb intake in perfect proportions? In new, groundbreaking research that is transforming our understanding of nutrition, animals from locusts to lions and yes, humans too, demonstrate the remarkable science behind appetite.

When attorney Chris Hansen learned that the U.S. government was issuing patents for human genes to biotech companies, his first thought was, How can a corporation own what makes us who we are? Then he discovered that women were being charged exorbitant fees to test for hereditary breast and ovarian cancers, tests they desperately needed—all because Myriad Genetics had patented the famous BRCA genes. So he sued them.

An entertaining deep dive into muscle, from the discovery of human anatomy to the latest science of strength training.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Dinosaurs. No other class of animals captures the hearts of both children and adults alike. Paleontologist Armin Schmitt brings us a firsthand account of the latest research on dinosaurs and their lives millions of years ago, including his spectacular global excavations and fascinating discoveries in the field. With the help of cutting-edge technology and unbelievable new finds, the age-old tale of the dinosaurs is now revitalized for the very first time, complete with astonishing illustrations by Ben Rennen that help us imagine dinosaurs like never before.

We are now on the doorstep of a fourth change brought about by two technologies: AI and robotics. The Fourth Age provides extraordinary background information on how we got to this point, and how - rather than what - we should think about the topics we’ll soon all be facing: machine consciousness, automation, employment, creative computers, radical life extension, artificial life, AI ethics, the future of warfare, superintelligence, and the implications of extreme prosperity.

Why do three out of four professional football players go bankrupt? How can illiterate jungle dwellers pass a test that tricks Harvard philosophers? And why do billionaires work so hard - only to give their hard-earned money away? When it comes to making decisions, the classic view is that humans are eminently rational. But growing evidence suggests instead that our choices are often irrational, biased, and occasionally even moronic. Which view is right - or is there another possibility?

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

Locked inside the DNA of every species that ever lived are endless stories - about origins, ancestors, fate, and much more. Until recently, these secrets were completely inaccessible. But with the help of new technologies, scientists are now reading the hidden history of DNA, making remarkable discoveries about ourselves and our fellow species. Your gateway to this treasure trove of information is Unlocking the Hidden History of DNA, 12 informative and accessible lectures delivered by New York Times best-selling author Sam Kean.

Resistance to malaria. Blue eyes. Lactose tolerance. What do all of these traits have in common? Every one of them has emerged in the last 10,000 years.

Maternal instinct - the all-consuming, utterly selfless love that mothers lavish on their children - has long been assumed to be an innate, indeed defining element of a woman's nature. But is it? In this provocative, groundbreaking audiobook, renowned anthropologist (and mother) Sarah Blaffer Hrdy shares a radical new vision of motherhood and its crucial role in human evolution. Hrdy strips away stereotypes and gender-biased myths to demonstrate that traditional views of maternal behavior are essentially wishful thinking codified as objective observation.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Did you know women walk more, eat less, socialize more, meet more men, dance more, and flirt more when they're ovulating? Or that PMS may have evolved to get rid of boyfriends with unfit sperm? Behind the "fickle" differences in what women find sexy about men, or what they like to wear, there's a hidden adaptive intelligence shaped over eons. Rather than making women irrational - as the conventional and irredeemably sexist wisdom goes - the female hormonal cycle has been exquisitely fine-tuned to give women the advantages they needed to succeed in our ancestral environments, and perhaps also today.

On the Origin of Species is one of the most important and influential books of its time and remains one of the most significant contributions to philosophical and scientific thought. The theories Darwin sets out here had an immediate and profound impact on the literature and philosophical thought of his contemporaries and continue to provoke thought and debate today. Written for the general public of the 1850s, On the Origin of Species laid out an evolutionary view of the world which challenged contemporary beliefs about divine providence and the fixity of species.

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo--Evolutionary Developmental Biology--is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

Among the estimated 100 billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.

In The Lost Family, journalist Libby Copeland investigates what happens when we embark on a vast social experiment with little understanding of the ramifications. Copeland explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.