Showing titles in Biotechnology

The full inside story of the breathtaking rise and shocking collapse of a multibillion-dollar start-up, by the prize-winning journalist who first broke the story and pursued it to the end. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose start-up ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood tests significantly faster and easier.

The Apples, Amazons and Googles of the next few decades will be biotech companies. The tech companies of the last few years have changed how we do things but the businesses driving the biotech revolution are about making life better. These companies will solve many of our most intractable problems: cancer, dementia, diabetes, elderly care, mental health challenges, even power generation and agricultural production. Biotech will mean that we can live far better, safer, healthier, wealthier, happier, and longer lives.

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

In The Patient Will See You Now, Eric Topol, one of the nation's top physicians, examines what he calls medicine's "Gutenberg moment". Much as the printing press liberated knowledge from the control of an elite class, new technology is poised to democratize medicine. In this new era, patients will control their data and be emancipated from a paternalistic medical regime in which "the doctor knows best."

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

De animales a dioses, augura un mundo no tan lejano en el cual nos veremos enfrentados a una nueva serie de retos. Homo Deus explora los proyectos, los sueños y las pesadillas que irán moldeando el siglo XXI - desde superar la muerte hasta la creación de la inteligencia artificial. Cuando tu smartphone te conozca mejor de lo que te conoces a ti mismo, ¿seguirás escogiendo tu trabajo, a tu pareja y a tu presidente?

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Penguin presents the unabridged, downloadable audiobook edition of The Future of the Mind by Michio Kaku, the international best-selling author of Physics of the Impossible. Read by the actor Feodor Chin. Recording memories, mind reading, videotaping our dreams, mind control, avatars, and telekinesis - no longer are these feats of the mind solely the province of overheated science fiction. As Michio Kaku reveals, not only are they possible, but with the latest advances in brain science and recent astonishing breakthroughs in technology, they already exist.

The microbiome is the missing link in modern medicine: a vast genetic universe of bacteria, yeasts, viruses and parasites that live inside us, influencing every aspect of our health, even the way we think and feel. In this mindblowing book, scientist and surgeon James Kinross explains how the organisms that live within us have helped us evolve, shaped our biology and defined the success of our species. With dazzling science and fascinating stories, this pioneering book will change the way you think about human health forever.

Humanity has reached a critical moment. Our world is unsettled and rapidly changing, and we face existential risks over the next century. Various outcomes - good and bad - are possible. Yet our approach to the future is characterized by short-term thinking, polarizing debates, alarmist rhetoric, and pessimism. In this short, exhilarating book, renowned scientist and best-selling author Martin Rees argues that humanity’s prospects depend on our taking a very different approach to planning for tomorrow.

Once, we humans could only observe evolution. Suddenly, we had conquered it. And yet, in Life as We Made It, evolutionary biologist Beth Shapiro argues that - despite how amazing our new technologies are - our ability to alter the course of evolution isn’t new. What is new is that where once we shaped evolution through brute force, we can now do it as artisans. That power comes not a moment too soon. If we are going to survive in the next few centuries, we must revise the book of life.

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Ein Blick durch das Schlüsselloch der Forschungslabore und Hightech-Firmen: Woran sie arbeiten, was sie planen, was jetzt schon möglich ist. Spitzenforscher sind sich einig: Auch mit Mitte 90 noch fit zu sein, kann Standard werden. Und 120 Jahre Leben wird für viele Menschen erreichbar – schon für die jetzt geborenen Generationen. Doch was müssen wir tun, um nicht nur länger zu leben, sondern auch länger gesund zu bleiben? Thomas Schulz, langjähriger SPIEGEL-Korrespondent im Silicon Valley, hat mit Konzernchefs und Spitzenforscherinnen, AI-Koryphäen und Medizinerinnen gesprochen.

A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.

The pharmaceutical drug discovery and development cycle is long and complex. This audiobook provides a concise overview of the whole process and offers insights into working in the pharmaceutical industry. It is ideal for individuals who are thinking about a career in this industry, as well as those who want to gain a general understanding of pharmaceutical drug discovery and development.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception―a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk untried new therapies.

A lo largo del último siglo, la humanidad ha logrado lo imposible frenando la hambruna, la peste y la guerra. Por primera vez en la historia, más personas mueren por obesidad que por pasar hambre y hay más probabilidades de quitarse la vida que de morir en un conflicto bélico o un atentado terrorista.

A riveting, fast-paced inside look at one of the most incredible private-sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr Albert Bourla, made 'the impossible possible' - creating, testing and manufacturing a safe and effective COIVD-19 vaccine that previously would have taken years to develop.

Biochemical engineering integrates the principles of biology, chemistry, and engineering to develop processes for the large-scale production of valuable biochemicals. This interdisciplinary field plays a crucial role in industries such as pharmaceuticals, biotechnology, food and beverage, and environmental engineering. One of the fundamental aspects of biochemical engineering is fermentation, which involves the controlled growth of microorganisms like bacteria, yeast, or fungi to produce desired compounds.

Este é um audiolivro de agricultura para filósofos e um audiolivro de filosofia para agricultores. Como nenhum de nós pode se abster de pensar ou de comer, todos deveríamos ser filósofos e agricultores em alguma medida. Sintropia é a tendência expressa pela vida de acumular e organizar energia, ou seja, uma força complementar à entropia.

The introduction of new medicines has dramatically improved the quantity and quality of individual and public health, while contributing trillions of dollars to the global economy. In spite of these past successes - and indeed because of them - our ability to deliver new medicines may be quickly coming to an end. Moving from the 20th century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy.

The Internet and smartphone are just the latest in a 250-year-long cycle of disruption that has continuously changed the way we live, the way we work, and the way we interact. The coming Augmented Age, however, promises a level of disruption, behavioral shifts, and changes that are unparalleled. While consumers today are camping outside of an Apple store waiting to be one of the first to score a new Apple Watch or iPhone, the next generation of wearables will be able to predict if we're likely to have a heart attack and recommend a course of action.

Millions of data enthusiasts from around the world compete on Kaggle, the most famous data science competition platform of them all. Participating in Kaggle competitions is a surefire way to improve your data analysis skills, network with an amazing community of data scientists, and gain valuable experience to help grow your career. The first audiobook of its kind, The Kaggle Book assembles in one place the techniques and skills you'll need for success in competitions, data science projects, and beyond.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them.