Showing titles in Contagious Diseases

In 2019, John Green met Henry, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone while traveling with Partners in Health. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal and dynamic advocate for increased access to treatment and wider awareness of the healthcare inequities that allow this curable, treatable infectious disease to also be the deadliest, killing 1.5 million people every year.

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

From a case of hysterical paralysis to a pregnancy puncturing a lung, twenty-five of the most thrilling medical mysteries known to man (and doctor)."Vital Signs," a popular column featured in Discover Magazine, has long been a favorite of readers, showcasing, each month, fascinating new tales of strange illnesses and diseases that baffle doctors and elude diagnosis. Each tale is true and borders on the unbelievable. It's no wonder that throughout the years the column has become an unofficial textbook for medical students, interns, doctors, and anyone interested in human illness and staying healthy.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens - both preexisting ones and those newly identified - emerge and reemerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what - if anything - can we do to stop them and their fatal march into our countries, our homes and our bodies?

Humanity is under assault from pandemics but not for the reasons that the mainstream sources portray. This book examines the claims regarding alleged “contagious” disease outbreaks such as COVID-19 to shed more light on what they are, or perhaps more importantly, what they are not. The belief that germs from the natural environment (or a laboratory) are attacking us has led most of the population to go along with lockdowns, civil rights restrictions, unprecedented peacetime censorship and more vaccines.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

On 26 March 2020, a new law appeared. In 11 pages, it locked down tens of millions of people, confined us to our homes, banned socialising, closed shops, gyms, pubs, places of worship. It restricted our freedoms more than any other law in history, justified by the rapid spread of a deadly new virus. You might have expected such a law to be fiercely debated in Parliament. But it wasn't debated at all. A state of emergency was declared, meaning the law came into force the moment it was signed.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

This global pandemic has disrupted life as we know it, in ways we could never have imagined. Even with the gradual easing of restrictions, many material challenges remain. The time has come to consider what happens next. If this experience has made you realise you want to prioritise different things from now on, and set yourself up so you feel less vulnerable to sudden change in future, We Are in This Together will help you do that.

In Phantom Plague, Vidya Krishnan, traces the history of tuberculosis from the slums of 19th-century New York to modern Mumbai. In a narrative spanning century, Krishnan shows how superstition and folk remedies made way for scientific understanding of TB, such that it was controlled and cured in the West.

In The Black Death: New Lessons from Recent Research, celebrated medievalist Dorsey Armstrong shares the fascinating new story of this old pandemic—revealed by dedicated researchers working with 21st-century technologies and a knowledge of language and history that now provide input from all geographic areas of the medieval world. In seven engaging lectures, Professor Armstrong corrects explanations of the pandemic that are now known to be inaccurate and offers a more robust description of plague biology than has ever been known.

In 1918, the world faced the deadliest pandemic in human history. What can the story of the so-called Spanish Flu teach us about the fight against present day crises and how to prepare for future outbreaks? At the height of WWI, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 months than AIDS killed in 24 years, more in a year than the Black Death killed in a century.

Mark Gober dives into fundamental beliefs about health and disease. These beliefs are so fundamental, in fact, that most of us probably haven’t thought to question them. For example, do bacteria cause disease, or are they part of the body’s cleanup crew that appears at the scene of an underlying toxicity or injury? Do researchers follow the scientific method when they claim to isolate viruses and show that they cause disease in their hosts? In addition to exploring these essential questions, Gober goes a layer deeper by examining the nature of consciousness.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

With the devastating effects of Covid-19 still rattling the foundations of our global civilization, we live in unprecedented times – or so we might think. But pandemics have been a constant presence throughout human history, as humans and disease live side by side. Over the centuries, our ability to react to these sweeping killers has evolved, most notably through the development of vaccines.

Multiple studies have now confirmed a dramatic link between the health of our microbiome—the trillions of bacteria that live in our digestive tract—and our likelihood of getting devastating viral illnesses like COVID-19. Low-fiber diets, limited exposure to nature, and overzealous use of pharmaceuticals have messed up our microbiome, making many of us more susceptible to viruses than we naturally should be.