Showing titles in Contagious Diseases

In 2019, John Green met Henry, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone while traveling with Partners in Health. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal and dynamic advocate for increased access to treatment and wider awareness of the healthcare inequities that allow this curable, treatable infectious disease to also be the deadliest, killing 1.5 million people every year.

Humanity is under assault from pandemics but not for the reasons that the mainstream sources portray. This book examines the claims regarding alleged “contagious” disease outbreaks such as COVID-19 to shed more light on what they are, or perhaps more importantly, what they are not. The belief that germs from the natural environment (or a laboratory) are attacking us has led most of the population to go along with lockdowns, civil rights restrictions, unprecedented peacetime censorship and more vaccines.

With over 17,000 known diseases affecting humans, and countless poisons, carcinogens and toxins in our environment, it's a miracle that our bodies manage to keep us alive. And that is, of course, if they don't betray us themselves, whether through cancers or autoimmune conditions. Biomedical researcher Professor John Tregoning tells the unlikely story of how, against all odds, we manage to stay alive. Taking an organ-by-organ tour of the human body, Tregoning embarks on his own experimental quest, testing 'life-extending' diets and exercise regimes to separate fact from fad.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

Multiple studies have now confirmed a dramatic link between the health of our microbiome—the trillions of bacteria that live in our digestive tract—and our likelihood of getting devastating viral illnesses like COVID-19. Low-fiber diets, limited exposure to nature, and overzealous use of pharmaceuticals have messed up our microbiome, making many of us more susceptible to viruses than we naturally should be.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens - both preexisting ones and those newly identified - emerge and reemerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world. How did these diseases come about? And what - if anything - can we do to stop them and their fatal march into our countries, our homes and our bodies?

Here is the story of SARS-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems, and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a 'forever virus,' destined to circulate among humans and bedevil us endlessly.

Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

In The Black Death: New Lessons from Recent Research, celebrated medievalist Dorsey Armstrong shares the fascinating new story of this old pandemic—revealed by dedicated researchers working with 21st-century technologies and a knowledge of language and history that now provide input from all geographic areas of the medieval world. In seven engaging lectures, Professor Armstrong corrects explanations of the pandemic that are now known to be inaccurate and offers a more robust description of plague biology than has ever been known.

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In Phantom Plague, Vidya Krishnan, traces the history of tuberculosis from the slums of 19th-century New York to modern Mumbai. In a narrative spanning century, Krishnan shows how superstition and folk remedies made way for scientific understanding of TB, such that it was controlled and cured in the West.

Reports suggest that over 100m people around the world are living with Long COVID (more than 1.5m in the UK) yet reliable, clear information and guidance remains scarce. This book is the definitive guide to understanding, managing and treating the condition. Written by the world's leading immunologist Professor Danny Altmann and expert patient Gez Medinger, The Long COVID Handbook translates cutting-edge science, patient-led research and practical guidance with clarity.

From a case of hysterical paralysis to a pregnancy puncturing a lung, twenty-five of the most thrilling medical mysteries known to man (and doctor)."Vital Signs," a popular column featured in Discover Magazine, has long been a favorite of readers, showcasing, each month, fascinating new tales of strange illnesses and diseases that baffle doctors and elude diagnosis. Each tale is true and borders on the unbelievable. It's no wonder that throughout the years the column has become an unofficial textbook for medical students, interns, doctors, and anyone interested in human illness and staying healthy.

On the eighth of February, Dr Dominic Pimenta encountered his first suspected case of coronavirus. Within a week, he began wearing a mask on the tube and within a month, he was moved over to the Intensive Care Unit to help fight the virus. Duty of Care is the first book to tell the full story of the COVID-19 pandemic from someone on the front line, working in one of the NHS's hardest hit areas.

As globalisation spreads and as we destroy the ancient ecosystems, we encounter strange and dangerous infections that originate in animals but that can be transmitted to humans. Diseases that were contained are being set free, and the results are potentially catastrophic. In a journey that takes him from Southern China to the Congo, from Bangladesh to Australia, David Quammen tracks these infections to their source and asks what we can do to prevent some new pandemic spreading across the face of the earth.

The origins of COVID-19 are shrouded in mystery. Scientists and government officials insisted, for a year and a half, that the virus had a natural origin, ridiculing anyone who dared contradict this view. Tech giants swept the internet, censoring and silencing debate in the most extreme fashion. Yet it is undeniable that a secretive facility in Wuhan was immersed in genetically manipulating bat-coronaviruses in perilous experiments. And as soon as the news of an outbreak in Wuhan leaked, the Chinese military took control and gagged all laboratory insiders.

This humbling and revelatory book shows how infectious disease has shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam. How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are.

In the middle of the second century AD, Rome was at its prosperous and powerful apex. The emperor Marcus Aurelius reigned over a vast territory that stretched from Britain to Egypt. The Roman-made peace, or Pax Romana, seemed to be permanent. Then, apparently out of nowhere, a sudden sickness struck the legions and laid waste to cities, including Rome itself. This fast-spreading disease, known now as the Antonine plague, may have been history’s first pandemic. Soon after its arrival, the Empire began its downward trajectory toward decline and fall.

From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

The plague that devastated Asia and Europe in the 14th century has been of never-ending interest to both scholars and the general public. Many books on the plague rely on statistics to tell the story. In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

In Vaxxers, we hear directly from Professor Gilbert and her colleague, Dr Catherine Green, as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm, they separate fact from fiction, they explain how they made a safe vaccine in record time with the eyes of the world watching and they give us hope for the future.

Rachel is a palliative care doctor who looked after some of the most gravely unwell patients on the COVID-19 wards of her hospital. Amid the tensions, fatigue and rising death toll, she witnessed the courage of patients and NHS staff alike in conditions of unprecedented adversity. For all the bleakness and fear, she found that moments that could stop you in your tracks abounded. People who rose to their best, upon facing the worst, as a microbe laid waste to the population. Her new book, Breathtaking, is an unflinching insider's account of medicine in the time of coronavirus.

With the devastating effects of Covid-19 still rattling the foundations of our global civilization, we live in unprecedented times – or so we might think. But pandemics have been a constant presence throughout human history, as humans and disease live side by side. Over the centuries, our ability to react to these sweeping killers has evolved, most notably through the development of vaccines.

In January 2020, as people started dying from a new virus in Wuhan, China, few really understood the magnitude of what was happening. Except, that is, a small group of scientific misfits who in their different ways had been obsessed all their lives with how viruses spread and replicated - and with why the governments and the institutions that were supposed to look after us, kept making the same mistakes time and again. This group saw what nobody else did. A pandemic was coming. We weren't prepared.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

Working in A&E is a challenging job, but nurse Louise Curtis loves it. She was newly qualified as an advanced clinical practitioner, responsible for life or death decisions about the patients she saw, when the unthinkable happened and the country was hit by the Covid-19 pandemic. The stress on the NHS was huge and for the first time in her life, the job was going to take a toll on Louise herself.