Showing titles in History & Commentary

This humbling and revelatory book shows how infectious disease has shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam. How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are.

The Tudor dynasty died out because there was no heir of Elizabeth I's body to succeed her. Henry VIII, despite his six marriages, had produced no legitimate son who would live into old age. Three of the reigning Tudors (Edward VI, Mary I, and Elizabeth I) died without heirs apparent, the most tragic case being that of Mary Tudor, who went through two recorded cases of phantom pregnancy. If it were not for physical frailty and the lack of reproductive health among the Tudors, the course of history might have been different.

Mark Gober dives into fundamental beliefs about health and disease. These beliefs are so fundamental, in fact, that most of us probably haven’t thought to question them. For example, do bacteria cause disease, or are they part of the body’s cleanup crew that appears at the scene of an underlying toxicity or injury? Do researchers follow the scientific method when they claim to isolate viruses and show that they cause disease in their hosts? In addition to exploring these essential questions, Gober goes a layer deeper by examining the nature of consciousness.

Witness early, bloody, anaesthetic-free operations and first crude surgical instruments, trace the mapping of the circulatory system, follow the painstaking detective work that led to the decoding of the human genome and understand the role that potions, cures, therapies, herbal medicines and drugs have played in the human quest to tame and conquer disease, injury and death. An engrossing history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

Since early 2020, the world has experienced a series of catastrophic events - a global pandemic caused by a so-called novel coronavirus; international lockdowns and border closings causing widespread business closures, economic collapse, and massive unemployment; and an unprecedented curtailment of civil liberties and freedoms in the name of keeping people safe by locking them up in their homes.

When it comes to illness, sometimes the end is just the beginning. Recovery and convalescence are words that exist at the periphery of our lives - until we are forced to contend with what they really mean. Here, GP and writer Gavin Francis explores how - and why - we get better, revealing the many shapes recovery takes, its shifting history and the frequent failure of our modern lives to make adequate space for it.

With poignant insight and humor, Frank Vertosick, Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick's patients and unsparing-yet-fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain illuminates both the mysteries of the mind and the realities of the operating room.

Over the past 50 years, rates of autoimmunity and chronic disease have exploded. In this provocative book, Dr. Thomas Cowan argues for a direct causal relationship to a corresponding increase in the number of vaccines American children typically receive. The goal of these vaccines is precisely what we’re now seeing in such abundance among our chronically ill children: the provocation of immune response. Cowan looks at emerging evidence that certain childhood illnesses are actually protective of disease later in life.

From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind's military technology had wildly surpassed its medical capabilities. The war caused carnage on an industrial scale and the nature of trench warfare meant that thousands sustained facial injuries. In The Facemaker, award-winning historian Lindsey Fitzharris tells the true story of the pioneering plastic surgeon Harold Gillies, who dedicated himself to restoring the faces of a brutalised generation.

In Patient Zero, Richard A. McKay presents a carefully documented and sensitively written account of the life of Gaetan Dugas, a gay man whose skin cancer diagnosis in 1980 took on very different meanings as the HIV/AIDS epidemic developed - and who received widespread posthumous infamy when he was incorrectly identified as patient zero of the North American outbreak.

New York City, 1929. A sanatorium, a deadly disease, and a dire nurse shortage. So begins the remarkable true story of the Black nurses who helped cure tuberculosis, one of the world's deadliest plagues, told alongside the often strange chronicle of the cure's discovery. Spanning the Great Depression and moving through World War II and beyond, this story follows the intrepid young women, the 'Black Angels', who, for twenty years, risked their lives working under dreadful conditions while caring for the city's poorest.

How to Survive a Plague by David France is the riveting, powerful and profoundly moving story of the AIDS epidemic and the grass-roots movement of activists, many of them facing their own life-or-death struggles, who grabbed the reins of scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease.

As a psychiatrist in training fresh from medical school, Carl Erik Fisher found himself face-to-face with an addiction crisis that nearly cost him everything. Desperate to make sense of his condition, he turned to the history of addiction, learning that our society’s current quagmire is only part of a centuries-old struggle to treat addictive behavior.

Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them "cells".

Picking up where Berton Roueche's The Medical Detectives left off, The Deadly Dinner Party presents 15 edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, MD, shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.

Drawing on Crampton’s own experience of surviving a life-threatening disease only to find herself beset by almost constant anxiety about her health, A Body Made of Glass explores part of the landscape of illness that most memoirs don’t reach: the territory beyond survival or cure, where body and mind seem locked in a strange and exhausting kind of dance. The result is both a fascinating cultural history of hypochondria and a moving account of what it means to live with this invisible, elusive and increasingly widespread condition.

Dripping with blood and gold, fetishised and tortured, gateway to earthly delights and point of contact with the divine, forcibly divided and powerful even beyond death, there was no territory more contested than the body in the medieval world. In Medieval Bodies, art historian Jack Hartnell uncovers the complex and fascinating ways in which the people of the Middle Ages thought about, explored and experienced their physical selves.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.