Showing titles in History & Commentary

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

Over the past 70 years, the Diagnostic and Statistical Manual of Mental Disorders, or DSM, has evolved from a virtually unknown and little-used pamphlet to an imposing and comprehensive compendium of mental disorder. Its nearly 300 conditions have become the touchstones for the diagnoses that patients receive, students are taught, researchers study, insurers reimburse, and drug companies promote.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

Blending fascinating history with lacerating wit, The Mystery of the Exploding Teeth will take you on a tour of some of the funniest, strangest and most wince-inducing corners of medical history. This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.

Thought of as the seat of our soul, then as a mysteriously animated object, the heart is still more a mystery than it is understood. Why do most animals only get one billion beats? (And how did modern humans get to over two billion - effectively letting us live out two lives?) Why are sufferers of gingivitis more likely to have heart attacks? And what does it really feel like to touch your own heart, or to have someone else's beating inside your chest?

Upon it's first publication 20 years ago, And The Band Played On was quickly recognized as a masterpiece of investigatve reporting. An international best seller, a nominee for the National Book Critics Circle Award, and made into a critically acclaimed movie, Shilts' expose revealed why AIDS was allowed to spread unchecked during the early 80's while the most trusted institutions ignored or denied the threat. One of the few true modern classics, it changed and framed how AIDS was discussed.

We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from 16th-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places.

While much has been written about the minds and methods of the medical professionals who save our lives, precious little has been said about their emotions. Physicians are assumed to be objective, rational beings, easily able to detach as they guide patients and families through some of life’s most challenging moments. But understanding doctors’ emotional responses to the life-and-death dramas of everyday practice can make all the difference on giving and getting the best medical care.

A comprehensive history of cancer – one of the greatest enemies of medical progress – and an insight into its effects and potential cures, by a leading expert on the illness. In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

Oliver Sacks died in August 2015 at his home in Greenwich Village, surrounded by his close friends and family. He was 82. He spent his final days doing what he loved: playing the piano, swimming, enjoying smoked salmon - and writing. As Dr Sacks looked back over his long, adventurous life his final thoughts were of gratitude. In a series of remarkable, beautifully written and uplifting meditations, in Gratitude Dr Sacks reflects on and gives thanks for a life well lived and expresses his thoughts on growing old, facing terminal cancer and reaching the end.

Wounded traces the journey made by a casualty from the battlefield to a hospital in Britain. It is a story told through the testimony of those who cared for him - stretcher bearers and medical officers, surgeons and chaplains, orderlies and nurses - from the aid post in the trenches to the casualty clearing station and the ambulance train back to Blighty. We feel the calloused hands of the stretcher-bearers; we see the bloody dressings and bandages; we smell the nauseating gangrene and, at London’s stations, the gas clinging to the uniforms of the men arriving home.

Shooting Up: A Short History of Drugs and War examines how intoxicants have been put to the service of states, empires, and their armies throughout history. Since the beginning of organized combat, armed forces have prescribed drugs to their members for two general purposes: to enhance performance during combat and to counter the trauma of killing and witnessing violence after it is over.

The stomach is notoriously outspoken. It growls, gurgles, and grumbles while other organs remain silent. For centuries humans have puzzled over this rowdy organ, deliberating on the extent of its influence over cognition, mental wellbeing, and emotions, and wondering how the gut became so central to our sense of self. Traveling from ancient Greece to Victorian England, eighteenth-century France to modern America, historian Elsa Richardson leads us on a tour of the gut, exploring all the ways that we have imagined, theorized, and probed the mysteries of the gastroenterological system.

The modern healthcare system has become proficient at staving off death with aggressive interventions. And yet, eventually everyone dies - and although most Americans say they would prefer to die peacefully at home, more than half of all deaths take place in hospitals or health care facilities. At the End of Life tackles this conundrum head on. Featuring 22 compelling personal-medical narratives, the collection explores death, dying, and palliative care, and highlights current features, flaws, and advances in the healthcare system.

Poppy tears, opium, heroin, fentanyl: humankind has been in thrall to the ‘Milk of Paradise’ for millennia. The latex of papaver somniferum is a bringer of sleep, of pleasurable lethargy, of relief from pain - and hugely addictive. A commodity without rival, it is renewable, easy to extract, transport and refine, and subject to an insatiable global demand. No other substance in the world is as simple to produce or as profitable. It is the basis of a gargantuan industry built upon a shady underworld, but ultimately it is a farm-gate material that lives many lives ....

It all started with a Hob Nob. As Dr Matt Morgan, an intensive care consultant, examined a patient who had suffered a cardiac arrest after inhaling some biscuit crumbs, he saw a flock of birds fly past the window. They must inhale objects all the time when flying, how do they survive? he thought to himself. This began an investigation that spanned continents, species and millennia. For animal science has so much to teach us about human medicine. While some of the overlaps and parallels are obvious, there is so much more that we have learnt from the animal world.

A world-renowned psychiatrist reveals the fascinating story of psychiatry's origins, demise, and redemption. Psychiatry has come a long way since the days of chaining "lunatics" in cold cells and parading them as freakish marvels before a gaping public. But as Jeffrey Lieberman reveals in his extraordinary and eye-opening book, the path to legitimacy for "the black sheep of medicine" has been anything but smooth.