Showing results for "memoir" in Genetics

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

In November 1987, a young couple on an overnight trip to Seattle vanished without a trace. A week later, the bodies of Tanya Van Cuylenborg and her boyfriend Jay Cook were found in rural Washington. It was a brutal crime, and it was the perfect crime: With few clues and no witnesses, an international manhunt turned up empty, and the sensational case that shocked the Pacific Northwest gradually slipped from the headlines.

In An Appetite for Wonder Richard Dawkins brought us his engaging memoir of the first 35 years of his life from early childhood in Africa to publication of The Selfish Gene in 1976, when he shot to fame as one of the most exciting new scientists of his generation. In Brief Candle in the Dark he continues his autobiography, following the threads that have run through the second half of his life so far and homing in on the key individuals, institutions and ideas that inspired and motivated him.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you.

Jamie Tyrone was 49 years old when she learned she had a 91% chance of getting Alzheimer's disease - by accident through genetic testing. She was shocked, but after an initial bout with depression she decided to take action rather than concede defeat. Jamie teamed up with Dr. Marwan Sabbagh, a renowned neurologist, and together they created a resource detailing not just Jamie's experience, but expert medical advice for anyone facing the disease.

This book will cover DNA links to convictions and acquittals. The long link of DNA evidence is vast. That many convictions were overturned because of DNA evidence or that many years after convictions individuals were set free. Privacy issues are also in question. Many countries have different regulations due to new laws surrounding the length of time that DNA is stored. The varying strands of this innovative forensic evidence collection is also in jeopardy.

Unravelling the Double Helix covers the most colourful period in the history of DNA, from the discovery of 'nuclein' in the late 1860s to the publication of Watson's The Double Helix in 1968. This is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar because the early history is largely neglected by books which focus on the episode of the double helix.

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

A biography of J. B. S. Haldane, the brilliant and eccentric British scientist whose innovative predictions inspired Aldous Huxley's Brave New World.

One in 3,000 people is born with neurofibromatosis. It affects all of them in different ways. For some, neurofibromatosis is as clear as the tumors on their face. For others, it hides beneath the surface, creating tumors that destroy hearing, vision, and more. Many of them are misdiagnosed, misunderstood, and often simply missed by a world of medicine that doesn't have a full grasp on all the effects of NF.

Walter Isaacson vertelt het verhaal van DNA-expert en Nobelprijswinnaar Jennifer Doudna. In oktober 2020 ontving biochemicus Jennifer Doudna samen met haar collega Emmanuelle Charpentier de Nobelprijs voor de Scheikunde voor hun doorslaggevende bijdrage aan de ontwikkeling van CRISPR-Cas. Met deze techniek kunnen wetenschappers het menselijk genoom bewerken door te knippen en plakken in DNA-sequenties.

Shortly before his father's death, Lennard Davis received a cryptic call from his uncle Abie, who said he had a secret he wanted to tell him one day. When finally revealed, the secret - that Abie himself was Davis's father, via donor insemination - seemed too preposterous to be true. Born in 1949, Davis wasn't even sure that artificial insemination had existed at that time. Moreover, his uncle was mentally unstable, an unreliable witness to the past. Davis tried to erase the whole episode from his mind.

Con el descubrimiento del ADN –el elemento básico de la vida– Crick y Watson influyeron en el desarrollo de la humanidad no solo en el ámbito científico, con la clonación y la investigación médica, sino también en nuestra vida diaria con la manipulación genética de los alimentos o la medicina forense. El descubrimiento del ADN también ha provocado serios dilemas éticos.