Showing results for "memoir" in Pharmacology

This is perhaps one of the best-loved of all journals. William Wordsworth's sister, Dorothy, began it in May 1800 and resolved to keep it for a short time. She continued it for nearly three years. In it, she brought the Dove Cottage years to vivid and intimate life. She noted the walks and weather, the friends, country neighbours, and travellers on the roads. She set down accounts of the garden, of Wordsworth's marriage, their concern for Coleridge, and the composition of Wordsworth's poetry.

The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.

Every catastrophe has a beginning. For the opioid crisis in America, the seed was a drug called OxyContin. First hailed as a miracle drug for severe pain in the early 1990s, OxyContin went on to ignite a plague of addiction and death across America. Equal parts crime thriller, medical detective story and business exposé, Pain Killer is the origin story of the opioid crisis, a hard-hitting look at how a supposed wonder drug became the trigger for a national tragedy.

For most of human history, mental illness has been largely untreatable. Sufferers lived their lives - if they survived - in and out of asylums, accumulating life's wreckage around them. In 1948, all that changed when an Australian doctor and recently returned prisoner of war, working alone in a disused kitchen, set about an experimental treatment for one of the scourges of mankind - manic depression, or bipolar disorder. That doctor was John Cade and in that small kitchen he stirred up a miracle.

Medicines are arguably the most highly regulated - and cost-inflated - products in the United States. The discovery, development, manufacturing, and distribution of medicines is carried out by an ever more complex and crowded set of industries, each playing a part in a larger “pharmaceutical enterprise” seeking to maximize profits. But this was not always the case. The Price of Health is the reveals the story of how the pharmaceutical enterprise took shape and led to the present crisis.

It’s the business of saving lives. Miracle Medicines goes behind the scenes of the pharmaceutical industry and into the high-security laboratories to tell the stories of the men and women - chemists, physiologists, medical and clinical researchers, engineers - who have chosen to toil for years in the lab in order to transform scientific theories into new lifesaving medicines. You’ll witness the day-to-day labors, victories and defeats of the dedicated professionals who are waging a war against the diseases that still plague mankind.

Seine Idee rettet Millionen Menschenleben. Im Jahr 1999 macht Ingmar Hoerr als Doktorand in einem Tübinger Labor eine überraschende Entdeckung: mRNA funktioniert als Impfstoff. Über zwanzig Jahre später schützt sich die Welt mit eben solchen mRNA-Impfstoffen vor dem Coronavirus: mit den Vakzinen von BioNTech, Moderna und CureVac. Zwischen Experiment und Triumph liegen zwei Jahrzehnte hartnäckigen Forschens. Mehrfach wäre Ingmar Hoerr mit CureVac fast gescheitert, hätte er nicht Dietmar Hopp, Bill Gates und Elon Musk von seiner Vision überzeugt.