• Targeting Longevity: NMN vs. NR for NAD+ Restoration

  • Jan 6 2025
  • Length: 9 mins
  • Podcast

Targeting Longevity: NMN vs. NR for NAD+ Restoration

Listen for free

View show details

  • Summary

  • In this episode of Daily Value, we look at science of Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR), two NAD+ precursors gaining traction in longevity research. Both supplements aim to restore NAD+ levels, critical for energy metabolism and cellular repair, yet their distinct pathways and tissue-specific effects suggest considerations for choosing one over the other.

    Discussion Points:

    -The metabolic pathways of NMN and NR, highlighting how their mechanisms of action influence NAD+ synthesis across tissues.

    -Insights from a 2024 study (in rodents - PMID: 38645109) demonstrating the dual effects of NMN: improvements in cardiac and liver function, alongside kidney inflammation linked to toxic metabolite accumulation at high doses.

    -Clinical dosing strategies, safety considerations, and how age and tissue-specific needs may guide the choice between NMN and NR.

    https://pubmed.ncbi.nlm.nih.gov/38645109/

    https://iadns.onlinelibrary.wiley.com/doi/10.1002/fft2.511

    Support the show
    Show More Show Less
Show More Show Less

What listeners say about Targeting Longevity: NMN vs. NR for NAD+ Restoration

Average customer ratings

Reviews - Please select the tabs below to change the source of reviews.

Audible.co.uk reviews

Amazon reviews
No Reviews are Available