In this episode, Dr. Dan Karlin, Chief Medical Officer at MindMed, talks about the potential of psychedelic therapies, especially LSD, to help treat anxiety. He shares his personal journey through psychiatry and addiction medicine, discussing the limitations of traditional treatments and the hope that psychedelics might bring. We dive into MindMed’s research on how LSD could impact generalized anxiety disorder (GAD), with Dr. Karlin explaining how it works and the importance of therapy alongside these treatments. This insightful conversation explores how MindMed is leading the way in developing new solutions for mental health, which could change the way we treat anxiety.

Today, we sit down with Robin and Dave Dubin from the AliveAndKickn Foundation, who share their inspiring journey with Lynch Syndrome. Robin explains the genetic intricacies of this hereditary cancer predisposition, emphasizing the crucial role of genetic counseling and the proactive measures taken for their children as previvors.

Dave, a three-time cancer survivor, offers an account of his experiences, shedding light on the motivations behind the foundation's establishment and the significance of patient advocacy. Together, they reveal how personal battles can transform into movements that champion patient-centric approaches in the healthcare landscape.

Topics Discussed:

(00:00:00) Introduction

(00:01:10) Robin’s background

(00:05:07) Screening for Lynch syndrome

(00:07:08) The history of the foundation and what it does

(00:09:10) The biggest challenges in raising awareness for Lynch Syndrome

(00:11:12) What is most effective in educating patients’ families on Lynch Syndrome

(00:12:25) Interacting with larger biopharma and biotech companies pursuing research in this space

(00:15:43) The vaccine for Lynch Syndrome

(00:19:29) Increasing awareness for older patients

(00:22:24) How the foundation tries to educate the clinical community

(00:26:43) The countries the foundation focuses on

(00:28:49) Helping patients communicate with their families

(00:32:46) How people can get involved and support AliveAndKickn

Links:

Robin Beth Dubin

Dave Dubin

In today's episode, Sasha Sinclair discusses the current challenges and emerging solutions shaping the future of patient recruitment and engagement in clinical trials. Sasha has a comprehensive background in clinical operations that allows her to share an informed perspective about how digital strategies and improved education can transform the landscape of clinical research, making it more accessible and inclusive for patients everywhere. She talks about the problem of patients not having access to trials and how to approach it, the new patient recruitment strategies she's excited about, and how the patient's journey affects the decisions made along the way.

Topics Discussed:

• (00:00:00) Introduction
• (00:00:56) Sasha’s background and her current role
• (00:02:38) Why patient recruitment is such a struggle currently
• (00:03:59) The ceiling on the percentage of providers that could feasibly do research and why it's limited
• (00:04:50) How to crack the problem of patients not having access
• (00:06:27) What an informal exchange of knowledge is and how it works for the patient