Episodes

  • Misconceptions About Catabolism of Glucose,Fat, & Amino Acids
    Dec 20 2024
    This podcast covers some misconceptions about catabolism of glucose , fat (Triacylglycerol) and amino acids. it also compares the energy output from these three dietary components.
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    13 mins
  • Integration of Metabolism: A Summary of Tissue Metabolism
    Dec 2 2024
    This podcast covers the major tissue effects of insulin and glucagon in the well-fed state and the fasting state, respectively. The key effects of these hormones on carbohydrate, fat, and protein metabolism in various tissues are summarized.
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    5 mins
  • Cell-Cell Communication
    Nov 17 2024
    Cell-Cell Communication is a fundamental process that is essential for the regulation of metabolism in various organs. Through hormones of the endocrine system, signals are chemically transmitted through the bloostream between different organs. The outcome of a hormone binding its specific receptor in target tissues can produce profound effects on metabolism. Insulin and its effects on the liver, is used as an example of the outcome of communication between the pancreas and the liver.
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    5 mins
  • Catabolism of Alanine, Glutamate & Aspartate
    Oct 29 2024
    This podcast covers the catabolism of alanine, glutamate and aspartate, including the roles of 3 important enzymes alanine transaminase (ALT), aspartate transaminase (AST) and glutamate dehydrogenage in this process. Input of nitrogen into the Urea cycle is provided directly or indirectly through the metabolism of the 3 discussed amino acids.
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    6 mins
  • Catabolism of Amino Acids: An Overview
    Oct 9 2024
    This podcast is an overview of the catabolism of amino acids including the initial phase of transferring amines through transaminases to an acceptor keto acid like Alpha-ketoglutarate to produce glutamate.
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    7 mins
  • Fatty acid mobilization from adipose tissue
    Sep 25 2024
    During fasting, fatty acids are mobilized from stored triacylglycerol in adipose tissue through the activation of Hormone-Sensitive Lipase by epinephrine which results in the release of 3 fatty acids to the bloodstream.
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    1 min
  • 3 Misconceptions About Dietary Fat
    Aug 31 2024
    This podcast covers three misconceptions dietary fat and covers the crucial contributions of dietary fat to energy production/ storage, membrane synthesis, and inflammation. The key roles of cholesterol in cellular functions are also summarized.
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    6 mins
  • Misconceptions About Glucose
    Aug 7 2024
    This podcast covers some misconceptions about glucose and its perceived bad effects on health. Glucose is an essential energy source for many tissues that almost exclusively depend on it availability in the bloodstream. In fact, through coordinated release of hormones and their various tissue effects, glucose is maintained between 80-100 mg/ dl during fasting and sleep with the purpose of supplying glucose to tissues that depend on it. Restoring blood glucose under fasting conditions is primarily accomplished by the liver. Although elevated plasma glucose can cause some health risks, the tissue requirement for glucose as an energy source can not be overlooked.
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    4 mins