Making Medicine

By: Incubate Coalition
  • Summary

  • There's a scientific breakthrough in your medicine cabinet. But how did it get there?

    At a time when medicines are helping us all live longer and healthier lives, this podcast will explore where these taken-for-granted miracles come from, how many of them almost never happened, where the life science ecosystem is taking us next, and most importantly, what it means for patients.

    From chance meetings that led to new ideas, to risky investments that never pay off, hear from the people behind today's and tomorrow's treatments, vaccines, technologies, devices, and yes, cures.

    In this golden age of health discovery and innovation fueled by record breaking investment in the life sciences, we'll bring guests who really understand what it means to be Making Medicine.
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Episodes
  • Can We Fix Healthcare? A Look Inside Our System
    Oct 15 2024
    The U.S. healthcare system is a puzzle for many.

    To fix it, we need smarter discussions and a deeper understanding of both the industry and the policies that shape it.

    In this episode, host John Stanford talks to healthcare policy expert Brian Reid, Principal at Reid Strategic and author of the Cost Curve newsletter, to discuss the challenges of fixing the incentives that have led to a broken healthcare system.

    We also discuss:
    • How the healthcare debate often overlooks the needs of patients, focusing instead on assigning blame to various system stakeholders.
    • The potential consequences price controls could have on pharmaceutical innovation (particularly for small molecules and cancer treatments).
    • Why the current healthcare environment discourages companies from investing in long-term R&D, particularly in drug types that primarily benefit the elderly.
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    19 mins
  • Protecting Innovation: Small Molecules and the Future of Medicine
    Sep 13 2024
    Science should lead our policy decisions—not the other way around.

    In this episode, Kirsten Axelson, Senior Policy Lab Advisor at Incubate Coalition, dives deep into the power of small molecule medicines, the promise they hold for the future, and how our current policy landscape may upend their development.

    This conversation focuses on Incubate Policy Lab’s most recent white paper, which sheds light on the crucial role these molecules play not only in innovative drug development, but also in ensuring equitable access to life-saving treatments.

    Listeners will learn:
    • ​​The crucial role small molecules play in modern medicine, especially in treating conditions like cancer and neurological diseases.
    • How current policy decisions, such as those in the Inflation Reduction Act, could negatively affect the development and accessibility of small molecule drugs.
    • Why small molecule medicines contribute to equitable access to healthcare, especially for underserved populations and in global health contexts.

    To learn more about Kirsten’s white paper, please go to incubatecoalition.org
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    18 mins
  • CEO Series Part 1: Sherine Chan, CEO & Co-founder of Neuroene Therapeutics
    Jun 28 2024
    As part of our inaugural CEO series, we're excited to welcome Sherine Chan, the CEO and Co-Founder of Neuroene Therapeutics.

    In this episode, Sherine shares her journey from academia to helming a cutting-edge biotech company. She explores the groundbreaking work her company is pioneering in targeting the powerhouses of cells: mitochondria. Sherine also dives into the influence of the Inflation Reduction Act on the development of small-molecule drugs

    We also discuss:
    • Neuroene Therapeutics' ongoing projects.
    • The critical role of mitochondrial dysfunction in neurological conditions such as epilepsy, Parkinson's, and mitochondrial disorders.
    • Sherine's insights for aspiring entrepreneurs and scientists.
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    17 mins

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