• In Silico Trials, Real Impacts

  • By: InSilicoUK
  • Podcast

In Silico Trials, Real Impacts

By: InSilicoUK
  • Summary

  • This is the official Podcast of the InSilicoUK Pro Innovation Regulations Network. We’re uniting visionaries from across all stakeholders to co-create an international strategy that fast-tracks virtual clinical trials, propelling healthcare innovation. Join us as we explore how computational modelling is reshaping patient care, boosting the economy, and accelerating medical breakthroughs. Tune in for insights on what in silico evidence is in medicine and how we can speed up its adoption. The future of healthcare is here – be part of the revolution.
    Copyright @ 2024 All rights reserved.
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Episodes
  • Cutting Costs, Boosting Results: The Tech Revolution in Clinical Trials
    Jan 27 2025

    Why are clinical trials becoming so expensive? Dive into the financial maze of skyrocketing costs, from patient recruitment challenges to decentralization hurdles. Discover how patient-centric strategies and digital tools are reshaping the landscape, cutting costs, and boosting efficiency. Join us as we uncover the hidden drivers behind these rising expenses and explore innovative solutions to optimize clinical trials. Don't miss it! DiMasi JA, Grabowski HG, Hansen RW. Innovation in the pharmaceutical industry: New estimates of R&D costs. J Health Econ. 2016 May;47:20-33.

    Moore TJ, Heyward J, Anderson G, Alexander GC. Variation in the estimated costs of pivotal clinical benefit trials supporting the US approval of new therapeutic agents, 2015-2017: a cross-sectional study. BMJ Open. 2020 Jun 11;10(6):e038863.

    MDGroup (2020) The True Cost Of Patient Drop-outs In Clinical Trials. https://mdgroup.com/blog/the-true-cost-of-patient-drop-outs-in-clinical-trials

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    15 mins
  • Breaking New Ground: The Virtual Trial Transforming Knee Surgery
    Jan 20 2025

    Can 3D-printed, personalized knee surgery implants revolutionize arthritis treatment? Virtual clinical trials show promising results for a custom device that could make corrective knee surgery safer and more accessible. Discover how computer simulations are paving the way for the future of personalized orthopaedics. MacLeod AR, Peckham N, Serrancolí G, Rombach I, Hourigan P, Mandalia VI, Toms AD, Fregly BJ, Gill HS. Personalised high tibial osteotomy has mechanical safety equivalent to generic device in a case-control in silico clinical trial. Commun Med (Lond). 2021 Jun 30;1:6. doi: 10.1038/s43856-021-00001-7.

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    12 mins
  • Standards as Innovation Catalysts: The PAGIT Framework
    Jan 13 2025

    How can we unlock innovation while ensuring responsible governance? Dive into the evolution of the PAGIT framework, where standards meet strategic oversight. From disruptive technologies to incremental advances, discover how this groundbreaking approach is reshaping the UK's innovation landscape. Join us to explore how smart regulation and standards are building tomorrow's technological future.

    Tait J (2024) The PAGIT framework: Its role in the governance of UK technologies to drive greater innovation, BSI, https://www.bsigroup.com/en-GB/insights-and-media/insights/whitepapers/update-to-pagit-framework-for-innovation.

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    38 mins

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