IM Journal Club

By: IM Journal Club
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  • Summary

  • Journal-Clubbing Our Way Through Internal Medicine


    Do you also find it hard to follow the medical literature?

    Newsletters with tables of contents are hard to get through after having written all your notes and maybe having done a chart dissection.


    Welcome to IM Journal Club!

    Our mission: to guide you through some of the most interesting internal medicine studies published in the last few weeks and months that you WOULD have liked to or SHOULD have heard about


    Target groups: physicians and other clinicians in general internal or family medicine – hospital medicine and primary care – or in an internal medicine subspecialty; biostatisticians, epidemiologists, or data scientists; journal club enthusiasts!


    Hidden agenda: to shed some lights on the studies’ methods AND on the context (what was known before, how do the new results change things – so what does this all mean?). We will give you episodes with primers on particularly difficult methods.


    We will come out with a new episode every one to two weeks - we'll upload early on Fridays - so you can listen on your commute or on the weekend.


    Please subscribe in your favorite podcast app or to our YouTube channel .


    Please let us know what we can do better, or what new study we could cover: You can leave a review in your podcasting app, a comment on YouTube, or drop us a line at hello@imjournalclub.com


    We are also on social; our email newsletter will be on Twitter: https://twitter.com/IMJournalClub


    ---

    Show Credits

    Host: Ben Geisler

    Video editor: Fernando Tábora

    Methods consultant: Professor Ulrich Mansmann

    Advisory group (current): Bijay Acharya, Chang-Berm Kang, Jeffrey L. Greenwald, Jonathan W. Heflin, Kathy May Tran, Marcel Müller, Rahul Ganatra, and Warren Chuang

    Supported by LMU Munich’s Institute for Epidemiology, Biometry, and Medical Information Processing


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    IM Journal Club
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Biological Sciences Hygiene & Healthy Living Physical Illness & Disease
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Episodes
  • Doxycycline for Community Acquired Pneumonia w/ Dr. Brad Spellberg

    Doxycycline for Community Acquired Pneumonia w/ Dr. Brad Spellberg
    Dec 23 2022

    Doxycycline is an old tetracycline-like antibiotic with a comparatively good side-effect profile, but it doesn’t get much love in the guidelines for community-acquired pneumonia as the evidence level was deemed to be low. A recent issue of Clinical Infectious Diseases contained a systematic review with a meta-analysis.

     

    Dr. Brad Spellberg is the chief medical office at the Los Angeles County-University of Southern California Medical Center. Dr. Spellberg is also a professor of clinical medicine and the associate dean for clinical affairs at the USC’s Keck School of Medicine.

     

    I talk with him about why doxy might be a good CAP drug (and when it is not a good choice), guidelines and the process of creating guidelines, and resistance patterns, MICs, and clinical significance.

     

    References:

    -Shorter Is Better: https://www.bradspellberg.com/shorter-is-better

    -Oral Is the New IV: https://www.bradspellberg.com/oral-antibiotics

    -WikiGuidelines: https://www.wikiguidelines.com/

    -SH Choi et al.: Clin Infect Dis. 2022 Jul 29;ciac615. https://pubmed.ncbi.nlm.nih.gov/35903011/

    -NICE: Pneumonia (community-acquired): antimicrobial prescribing. Published: 16 September 2019. https://www.nice.org.uk/guidance/ng138

    -JP Metlay et al. Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST. https://pubmed.ncbi.nlm.nih.gov/31573350/

     

    YouTube channel: https://www.youtube.com/@IMJournalClub


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    18 mins
  • Colonoscopy For Colorectal Cancer Screening: NordICC w/ Dr. Michael Bretthauer

    Colonoscopy For Colorectal Cancer Screening: NordICC w/ Dr. Michael Bretthauer
    Dec 16 2022

    The NordICC Study is the first randomized controlled trial to test colonoscopy as a screening modality for colorectal cancer. The effect of colonoscopy was lower than previously thought.

    We talk with the P.I., Dr. Michael Bretthauer, what to make of the study and whether (and in which areas) we should remain doubtful. Dr. Bretthauer is a professor of medicine at the University of Oslo.

     

    References:

    • M Bretthauer et al. N Engl J Med. 2022 Oct 27;387(17):1547-1556. https://pubmed.ncbi.nlm.nih.gov/36214590/
    • RL Siegel et al. CA Cancer J Clin. 2022;72:7-33. https://pubmed.ncbi.nlm.nih.gov/35020204/
    • Ø Holme et al. Ann Intern Med. 2018;168:775-82. https://pubmed.ncbi.nlm.nih.gov/29710125/
    • Global Cancer Observatory, https://gco.iarc.fr/
    • M Bretthauer et al. Ann Int Med. 2017;166:139-40. https://pubmed.ncbi.nlm.nih.gov/27820949/
    • USPSTF: JAMA. 2021;325(19):1965-77 https://jamanetwork.com/journals/jama/fullarticle/2779985
    • E Quintero et al. N Engl J Med. 2012;366:697-706 https://pubmed.ncbi.nlm.nih.gov/22356323/
    • AB Knudsen et al. JAMA. 2021;325(19):1998-2011 https://pubmed.ncbi.nlm.nih.gov/34003219/
    • Ex. calculator: https://ccrisktool.cancer.gov/calculator.html
    • LM Helsingen et al. BMJ. 2019367:l5515. https://pubmed.ncbi.nlm.nih.gov/31578196/

     

    YouTube: https://youtu.be/mTxKbbcx9BY


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    31 mins
  • Some ideas for the next episodes

    Some ideas for the next episodes
    Dec 2 2022

    Here's our ideas, please cast your vote: https://www.youtube.com/@IMJournalClub/community


    While you're on the channel page, please also subscribe: https://www.youtube.com/@IMJournalClub?sub_confirmation=1


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    1 min

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