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Today we’re diving into the exciting world where genetics meets pharmacology. Dr. Emily Cicali will uncover the mysteries of pharmacogenomics (PGX) and explain how your DNA influences your response to medications. Get ready for insights, real-world applications, and a touch of scientific magic!

Emily J. Cicali, Pharm.D., earned her Doctor of Pharmacy from Philadelphia College of Pharmacy in 2015. She completed a Pharmacy Residency at Tabula Rasa HealthCare in Geriatric Personalized Medicine. Afterward, she joined Tabula Rasa HealthCare as a Research Pharmacist and adjunct faculty, focusing on pharmacokinetics and pharmacogenomics.

In 2017, she transitioned fully into academia, completing a pharmacogenomics fellowship at the University of Florida. Cicali is now a Clinical Associate Professor, runs a virtual pharmacogenetics consultation service called MyRx, and focuses on implementing pharmacogenomics and studying phenoconversion for medication safety.

Highlights of the Episode:

• Pharmacogenomics 101: Discover how this DNA test focuses on liver enzymes to predict your response to medications.
• Why It Matters: Learn how understanding your genetics can reduce trial-and-error in prescribing, especially for depression and anxiety.
• Emily’s Journey: Follow Emily’s path from a student fascinated by genetics to an expert in PGX, highlighting her passion and success.
• Clinical Research Impact: Hear about Emily’s role in clinical trials and how PGX testing is improving patient outcomes in pain and mental health management.

Key Takeaways:

• Personalized Medicine: Understand the importance of personalized medication therapy and how PGX can help tailor treatments to individual patients for better efficacy and fewer side effects.
• Real-Life Applications: Learn about the real-world implications of PGX testing, from reducing opioid use in pain management to improving outcomes for heart attack patients.
• Patient Empowerment: Emily emphasizes the role of PGX in empowering patients by giving them more control over their healthcare and improving communication with providers.

Episode Highlights:
[0:54] Emily explains pharmacogenomics and its significance.
[2:09] The benefits of knowing your genetic makeup before starting medication.
[3:25] Emily’s career journey and her passion for genetics and pharmacy.
[6:34] How PGX testing is integrated into clinical practice at MyRx.
[10:54] Emily’s experience in clinical research and the impact of PGX on patient outcomes.
[17:39] The mechanism of drug metabolizing enzymes and their role in medication efficacy.
[20:23] How to discuss PGX testing with your doctor and insurance considerations.
[26:08] Real-life success stories and patient experiences with PGX.
[30:26] Emily’s hopes for the future of PGX and its broader implementation in healthcare.
[36:43] Resources and advice for listeners interested in PGX testing.

📞 Connect with Dr. Emily Cicali:
Website: https://ufhealth.org/myrx/
Email: MyRx@cop.ufl.edu
Phone: 352-273-6415
LinkedIn: https://www.linkedin.com/in/emily-cicali-pharmd-2164b2a4/

📞 Connect with Suzanne:

• Website: https://www.iceconsultingllc.com/home
• LinkedIn: https://www.linkedin.com/in/turnersuzannem/

💌 Feedback and Questions:

• Email Suzanne at podcast@iceconsultingllc.com

🎙️ Tune in and get to know the passionate professional behind Heart of the Trial!