Our guest for Episode 10 is Dr. Amanda Jacobson Kelly, who is an assistant professor of pediatrics in the division of hematology oncology at Nationwide Children's Hospital and the Ohio State University College of Medicine. Dr. Jacobson Kelly will be continuing the conversation from Episode 9: Let’s Iron It Out, focusing this time on intravenous (IV) iron.

In our ninth podcast, "Let's Iron it Out", Our guest is Dr. Amanda Jacobson-Kelly, who is an assistant professor of pediatrics in the division of hematology oncology at Nationwide Children's Hospital and the Ohio State University College of Medicine. We will discuss the diagnosis and management of iron deficiency and iron deficiency anemia.

In our 8th episode, we continue the conversation from Episode 7: Reproductive Health and Sickle Cell Disease. Joining our hosts, Dr. Sweta Gupta and Dr. Tricia Huguelet, are two guests – Dr. Zachary Ramsay and Dr. Christy Bemrich-Stolz, who share their experience both as researchers and clinicians in treating sickle cell disease.

Dr. Ramsay is a physician and clinician epidemiologist at the University of the West Indies in Kingston, Jamaica. A recipient of an FWGBD Research Fellowship Award, he continues to investigate the influence of sex hormones on pain among women with sickle cell disease.

Dr. Christy Bemrich-Stolz is an Associate Professor in the Division of Pediatric Hematology and Oncology at the University of Alabama at Birmingham and is an active WGSCD LAN member.

Although we have made leaps and strides in the treatment of sickle cell disease with the development of several disease-modifying medications and gene therapies, as physicians we still grapple with basic health issues, specifically for young girls and women, including – menstrual pain, fertility, maintaining a healthy pregnancy, and positive outcomes for mother and baby.

Joining our host for this episode is guest co-host, Dr. Tricia Huguelet. Dr. Huguelet is a pediatric gynecologist, who serves alongside Dr. Gupta as Co-Chair for the Education and Advocacy Subcommittee for the WGBD LAN. Dr. Deva Sharma, an Assistant Professor at Vanderbilt University Medical Center, joins our hosts to discuss sickle cell disease and its impact on reproductive health.

As we closed 2023, the Food and Drug Administration (FDA) approved two gene therapies to treat sickle cell disease (SCD). These potential curative therapies include CASGEVY™ (exagamglogene autotemcel [exa-cel]) from Vertex Pharmaceuticals Incorporated and CRISPER Therapeutics, and LYFGENIATM from bluebirdbio. While there is a lot of excitement for these advances, the impacts of these therapies are not currently known. Like with many therapies, the impact on women and their future fertility are among the unknowns and are areas of concern for individuals living with sickle cell disease and their healthcare providers.

Please join 7-2-1 for this special edition episode, How New Gene Therapies for SCD May Impact Women’s Fertility, with WGSCD LAN Chair, Dr. Alecia Nero, and special guest, Dr. Kelly Acharya, a Reproductive Endocrinologist, and Infertility Specialist with Duke Health. Together, they discuss the areas of concern for women and girls living with SCD and consider what the future may hold for those who are able to receive these life-changing treatments so that they may stay informed in the decision-making process.

As physicians taking care of young girls and women with HMB, we are often faced with a challenging patient who is at a high risk for developing thrombosis due to a family history, a past personal history of thrombosis or medical conditions that could be a trigger for developing blood clots. In this podcast, we will be speaking with our experts on thrombosis and HMB to help us navigate through these difficult decision-making scenarios. We will be referring to certain brand names of hormonal therapies as our listeners are familiar with those rather than the complicated generic nomenclature. We will use gender-neutral language whenever possible, but when discussing the results of clinical studies, we may refer to women or girls because that is the language specifically used by the authors.

The pill aka “oral contraceptive pill, OCP “, “birth control pill” is a misnomer when used solely for HMB by a pre-teen or teenager and unfortunately, can be associated with a stigma. In the true sense, pill used for heavy period flow is in fact hormonal therapy. We will be referring to the pill also as hormonal therapy during this discussion and will clarify several misconceptions about it, thereby hoping for a wider acceptance of these medications.

To dispel these stigmas, we have our esteemed guest Dr. Janice Bacon, who is a general obstetrician & gynecologist with a sub-specialty certification in pediatric and adolescent gynecology. She is currently in private practice at Lexington Medical Center and is a Clinical Professor of Obstetrics and Gynecology for the University of South Carolina, School of Medicine in Columbia. Dr. Bacon has a strong interest and background in helping patients with menstrual problems. She is the past president of the North American Society for Pediatric and Adolescent Gynecology (NASPAG) and currently serves on the board of directors and education committee for the Foundation for Women and Girls with Blood Disorders (FWGBD).

In this episode, your hosts continue to explore some great information and facts about the use of IUDs for heavy menstrual bleeding and are joined by a well-known expert in the fields of adolescent medicine and reproductive health, Dr. Claudia Borzutzky.