Showing titles in Genetics

Sir Paul Nurse is one of Britain's greatest living scientists. Here he invites listeners on a journey of discovery of biology's five great building blocks including The Cell, The Gene, Evolution by Natural Selection, Life as Chemistry, Life as Information and then an inspiring piece on how we can change the world with this knowledge. Accessible and easy to listen to, Paul's engaging, personal tone will make listeners light up with excitement as they learn how all living beings are connected.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, and agricultural chemistry as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact on our society and our world.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Red is a brilliantly told, captivating history of red hair throughout the ages. An audiobook that breaks new ground, dispels myths, and reinforces the special nature of being a redhead, with a look at multiple disciplines, including science, religion, politics, feminism and sexuality, literature, and art. With an obsessive fascination that is as contagious as it is compelling, author Jacky Colliss Harvey (herself a redhead) begins her exploration of red hair in prehistory and traces the redhead gene as it made its way out of Africa with the early human diaspora.

She Has Her Mother’s Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities....

Humanity has often found itself on the precipice. We've survived and thrived because we've never stopped moving. In this eye-opening book, Johannes Krause, chair of the Max Planck Institute for the History of Humanity, offers a new way of understanding our past, present and future. Marshalling unique insights from archaeogenetics, an emerging new discipline that allows us to read our ancestors' DNA like journals chronicling personal stories of migration, Krause charts two millennia of adaption, movement and survival.

Nothing is more familiar and yet less understood than the human mind. It defines the experience of being human, and yet its workings contain some of the deepest mysteries ever encountered. Written by one of the world's greatest teachers of psychology, The Human Mind provides a masterful and riveting guide to all that we have learned since modern science began probing those mysteries.

What makes you the way you are - and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains.

World renowned scientist Carl Sagan and acclaimed author Ann Druyan have written a Roots for the human species, a lucid and riveting account of how humans got to be the way we are. It shows with humor and drama that many of our key traits - self-awareness, technology, family ties, submission to authority, hatred for those a little different from ourselves, reason, and ethics - are rooted in the deep past, and illuminated by our kinship with other animals.

For over a century we saw Neanderthals as inferior to Homo Sapiens. After new discoveries, the pendulum swung the other way and they are generally seen as our relatives: not quite human, but similar enough, and still not equal. Now, thanks to an ongoing revolution in palaeoanthropology in which he has played a key part, Ludovic Slimak shows us that they are something altogether different - and they should be understood on their own terms rather than by comparing them to ourselves. As he reveals in this stunning book, the Neanderthals had their own history, their own rituals, their own customs.

Perched on the exterior of our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerisingly complex world of micro-organisms, its physical functions are vital to our health and indeed our survival, and it's crucial to our sense of identity. Yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey through the comedy, tragedy and exquisite humanity of our most underrated and overlooked organ.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

Our understanding of the ‘tree of life’, with powerful implications for human genetics, human health and our own human nature, has recently completely changed. This book is about a new method of telling the story of life on earth - through molecular phylogenetics. It involves a fairly simple method - the reading of the deep history of life by looking at the variation in protein molecules found in living organisms. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.